2.1 Biomolecules: Chemistry of Steroids

Biomolecules:
I. Chemistry of Steroids
2.1 Definition of steroids and sterols, numbering and ring letters, orientation of projection formulae, stereochemistry of ring junction and side chain attachments, stereochemistry of substituents in the side chain.
2.2 Types of steroid hormones: androgens, estrogens, progestins, corticosteroids. Structure and biosynthesis of steroids from cholesterol. Confirmation and chemical reactivity, steroid specific reactions of A and B rings, Addition-elimination, epoxide opening, relative rates of esterification, oxidation of epimeric alcohols, reduction of ketones.

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