1.5 Fused heterocycles with One heteroatom: Quinoline, Isoquinoline & Indole

1.5
Fused heterocycles with One heteroatom
a. Quinoline: Synthetic methods including Skraup synthesis, Doebner-Miller synthesis, Friedlander synthesis, Conrad-Limpach synthesis. Reactions with acids, Electrophilic Aromatic Substitution (EAS), nucleophiles, oxidizing and reducing agents
b. Isoquinoline: Synthetic methods including Bischler-Napieralski and Pomeranz-Fritsch, Reactions including EAS, nucleophiles, oxidizing and reducing agents.
c. Indole: Synthesis by Fischer indole synthesis, Madelung synthesis. Reactions with acids, EAS, Metallic K, Mannich reaction, oxidizing and reducing agents.


Quinoline, Isoquinoline

 Indole

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